Clinical studies

The goal of clinical studies is to evaluate and introduce new cancer treatments. Clinical studies are conducted within or under the auspices of international associations, as EU-funded projects, as studies sponsored by pharmaceutical companies, or as a result of our own research.

Breast cancer

Code	Title	Principal Investigator at the Institute of Oncology
TAORMINA	Treatment of oligometastatic breast cancer – a randomized Phase 3 study comparing stereotactic ablative radiotherapy combined with systemic treatment versus systemic treatment alone as first-line treatment	Ivica Ratoša
GALIA	Studying the role of circulating tumour cell clusters in patients with high-risk early breast cancer	Cvetka Grašič Kuhar
/	Diagnostic significance of BRCA1, RASSF1A and PTEN gene methylation in lesions of uncertain malignant potential	Romi Cencelj
PionERA	Open-label, randomised Phase III study to evaluate the efficacy and safety of giredestrant compared with fulvestrant, both in combination with a CDK4/6 inhibitor, in patients with ER-positive, HER2-negative advanced breast cancer	Simona Borštnar
Onko-Adher	Participation of patients with early hormone-dependent, HER2-negative breast cancer in adjuvant treatment with aromatase inhibitors with or without abemaciclib	Erika Matos

Respiratory cancers

No news available.

Gastrointestinal cancer

Code	Title	Principal Investigator at the Institute of Oncology
/	Efficacy of combined chemotherapy and ablative stereotactic radiotherapy (SBRT) as first-line treatment for locally advanced inoperable pancreatic cancer	Janja Ocvirk
PILDI	Effect of perioperative intravenous infusion of lidocaine or high-dose dexamethasone on the immune response in patients undergoing surgery for colon cancer – the PILDI study	Nikola Bešič
APERIO	Multicentre randomized clinical study on the impact of using the Ready4OP application before major oncological surgery on patients’ health literacy	Gašper Pilko

Skin cancers

Code	Title	Principal Investigator at the Institute of Oncology
INSPECT	European database of electrochemotherapy – INSPECT (registry)	Gregor Serša, Marko Snoj
/	Electrochemotherapy Induces Changes in Tumor Microenvironment of Cutaneous and Subcutaneous Metastases in Patients with Cutaneous Melanoma	Barbara Perić

Urinary tract cancer

No news available.

Gynecological cancer

Code	Title	Principal Investigator at the Institute of Oncology
/	Use of electrochemotherapy in women with vulvar cancer	Sebastjan Merlo

Solid tumors

Code	Title	Principal Investigator at the Institute of Oncology
OligoCare	E²-RADIatE – OligoCare: A pragmatic observational cohort study to evaluate radical radiotherapy for oligo-metastatic cancer patients	Ivica Ratoša
ReCare	E²-RADIatE: EORTC-ESTRO Radiotherapy Infrastructure for Europe, ReCare cohort – 2011	Staša Jelerčič
pRevenT	A Randomised Controlled Trial of (Early) Prophylactic Radiotherapy to Prevent Bone Complications in Patients with Metastatic Solid Cancers (pRevenT)	Jasna But Hadžić

Head and neck cancers

Code	Title	Principal Investigator at the Institute of Oncology
/	Assessment of the effect of hyperbaric oxygenation on parotid gland function after radiotherapy for head and neck cancer using magnetic resonance imaging	Primož Strojan

Sarcomas

Code	Title	Principal Investigator at the Institute of Oncology
/	SI-SARK Registry	Marko Novak
RESAR	Retroperitoneal Sarcoma Registry (RESAR): prospective collection of patient data and radiological and pathological material for the TransAtlantic Retroperitoneal Sarcoma Working Group	Marko Novak

Prostate cancer

Code	Title	Principal Investigator at the Institute of Oncology
miRNA	Use of miRNA to Predict Therapy Response and Acute Toxicity to Radiotherapy in Patients with Prostate Cancer: Clinical Implementation of miRNA for Personalised Therapy	Blaž Grošelj

Other studies

Code	Title	Principal Investigator at the Institute of Oncology
GENTURIS Registry	European registry of patients with hereditary tumour predisposition syndromes operating within ERN GENTURIS	Mateja Krajc
MUH	Programme for Improvement of Malignant Spinal Cord Compression Treatment in Slovenia	Barbara Šegedin
/	Independent and supervised drainage of symptomatic ascites with a central venous catheter	Gregor Vivod
STOPSTORM	European registry for observational and prospective data collection on stereotactic radiotherapy for ventricular tachycardia	Jasna But Hadžić
/	Analysis of Malfunctions of Implanted Electronic Devices in Patients Undergoing Radiotherapy	Irena Oblak
TENSINTEST	Angiotensin II Stress Test (TENSINTEST): Kinetics of Renin During Treatment of Vasoplegic Shock with Angiotensin II in Connection with Hemodynamic Response to Treatment with Angiotensin II	Milena Kerin Povšič

Name	Purpose	Lifetime
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_pk_ref	Tracking from which sites users come to our web pages.	6 months
_pk_ses	Counting web site visits.	30 minutes
_ga	Used to distinguish users.	2 years
_ga_--container-id--	Persists session state.	2 years

Programs, Projects and Studies